Clinical neurology and neurosurgery · 2013
Collagen-only biomatrix as dural substitute: What happened after a 5-year observational follow-up study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Esposito Felice, Grimod Gianluca, Cavallo Luigi M, Lanterna Luigi, Biroli Francesco, Cappabianca Paolo
Аннотация
OBJECTIVES: To assess long-term efficacy of the collagen-only biomatrix as a dural substitute in a large case series.
PATIENTS AND METHODS: We reviewed a prospectively acquired database of patients who underwent neurosurgical surgeries in whom the dural substitute was used and who were the subject of two previous studied with shorter follow-ups.
RESULTS: The present study was conducted on 111 subjects of the original 209 patients. No late complications, nor local or systemic toxicity were observed during the observational period. As a matter of facts, 5 patients (4.5%) underwent reoperation for different reasons and 2 out of 5 experienced subcutaneous fluid collections; another case (0.9%), already reported in our previous studies, developed a CSF leak after an endoscopic endonasal operation for an intra-suprasellar arachnoid cyst.
CONCLUSIONS: Our data further confirm that the collagen-only biomatrix derived from horse equine tendon is a safe and effective dural substitute for routine neurosurgical procedures.
PATIENTS AND METHODS: We reviewed a prospectively acquired database of patients who underwent neurosurgical surgeries in whom the dural substitute was used and who were the subject of two previous studied with shorter follow-ups.
RESULTS: The present study was conducted on 111 subjects of the original 209 patients. No late complications, nor local or systemic toxicity were observed during the observational period. As a matter of facts, 5 patients (4.5%) underwent reoperation for different reasons and 2 out of 5 experienced subcutaneous fluid collections; another case (0.9%), already reported in our previous studies, developed a CSF leak after an endoscopic endonasal operation for an intra-suprasellar arachnoid cyst.
CONCLUSIONS: Our data further confirm that the collagen-only biomatrix derived from horse equine tendon is a safe and effective dural substitute for routine neurosurgical procedures.
Предметные рубрики MeSH
AdultBiocompatible MaterialsBrain NeoplasmsCerebrospinal Fluid LeakCerebrospinal Fluid RhinorrheaCollagenDura MaterFemaleFibrin Tissue AdhesiveFollow-Up StudiesHumansMagnetic Resonance ImagingMaleNeurosurgical ProceduresPostoperative PeriodProspective StudiesReoperationTissue AdhesivesTreatment Outcome