Surgical innovation · 2011
Role of chemoembolization as a rescue treatment for recurrence of resected hepatoblastoma in adult patients.
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Di Benedetto Fabrizio, Di Sandro Stefano, D'Amico Giuseppe, De Santis Mario, Gerunda Giorgio Enrico
Аннотация
INTRODUCTION: Hepatoblastoma is the most common malignant liver tumor in children, but it is extremely rare in adults.
MATERIALS AND METHODS: A 33-year-old man was admitted with nausea, vomiting, weight loss, and right upper quadrant pain. A preoperative magnetic resonance imaging showed a nodular hepatic lesion infiltrating the lesser curvature of the stomach. A left hepatectomy and a subtotal gastrectomy were performed. The histological diagnosis was hepatoblastoma. A recurrence in the right lobe was seen.
RESULTS: Three cycles of transcatheter arterial chemoembolization (TACE) were performed 40, 70, and 130 days after surgery. No sign of recurrence was present at the time of the second chemoembolization.
CONCLUSION: The TACE was well tolerated by the patient and controlled the recurrence. The patient survived 11 months after recurrence of disease and died 1 year after the liver resection. The use of TACE to treat the hepatic recurrence was never described.
MATERIALS AND METHODS: A 33-year-old man was admitted with nausea, vomiting, weight loss, and right upper quadrant pain. A preoperative magnetic resonance imaging showed a nodular hepatic lesion infiltrating the lesser curvature of the stomach. A left hepatectomy and a subtotal gastrectomy were performed. The histological diagnosis was hepatoblastoma. A recurrence in the right lobe was seen.
RESULTS: Three cycles of transcatheter arterial chemoembolization (TACE) were performed 40, 70, and 130 days after surgery. No sign of recurrence was present at the time of the second chemoembolization.
CONCLUSION: The TACE was well tolerated by the patient and controlled the recurrence. The patient survived 11 months after recurrence of disease and died 1 year after the liver resection. The use of TACE to treat the hepatic recurrence was never described.
Предметные рубрики MeSH
AdultAntineoplastic Combined Chemotherapy ProtocolsBiopsy, NeedleChemoembolization, TherapeuticCisplatinDoxorubicinFollow-Up StudiesHepatectomyHepatoblastomaHumansImmunohistochemistryLaparotomyLiver NeoplasmsMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalRemission InductionRisk AssessmentSecond-Look SurgeryTreatment Outcome