Sleep · 2014
Delusional confusion of dreaming and reality in narcolepsy.
СтатьяМногоцентровое исследованиеПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Wamsley Erin, Donjacour Claire E H M, Scammell Thomas E, Lammers Gert Jan, Stickgold Robert
Аннотация
STUDY OBJECTIVES: We investigated a generally unappreciated feature of the sleep disorder narcolepsy, in which patients mistake the memory of a dream for a real experience and form sustained delusions about significant events.
DESIGN: We interviewed patients with narcolepsy and healthy controls to establish the prevalence of this complaint and identify its predictors.
SETTING: Academic medical centers in Boston, Massachusetts and Leiden, The Netherlands.
PARTICIPANTS: Patients (n = 46) with a diagnosis of narcolepsy with cataplexy, and age-matched healthy healthy controls (n = 41).
INTERVENTIONS: N/A.
MEASUREMENTS AND RESULTS: "Dream delusions" were surprisingly common in narcolepsy and were often striking in their severity. As opposed to fleeting hypnagogic and hypnopompic hallucinations of the sleep/wake transition, dream delusions were false memories induced by the experience of a vivid dream, which led to false beliefs that could persist for days or weeks.
CONCLUSIONS: The delusional confusion of dreamed events with reality is a prominent feature of narcolepsy, and suggests the possibility of source memory deficits in this disorder that have not yet been fully characterized.
DESIGN: We interviewed patients with narcolepsy and healthy controls to establish the prevalence of this complaint and identify its predictors.
SETTING: Academic medical centers in Boston, Massachusetts and Leiden, The Netherlands.
PARTICIPANTS: Patients (n = 46) with a diagnosis of narcolepsy with cataplexy, and age-matched healthy healthy controls (n = 41).
INTERVENTIONS: N/A.
MEASUREMENTS AND RESULTS: "Dream delusions" were surprisingly common in narcolepsy and were often striking in their severity. As opposed to fleeting hypnagogic and hypnopompic hallucinations of the sleep/wake transition, dream delusions were false memories induced by the experience of a vivid dream, which led to false beliefs that could persist for days or weeks.
CONCLUSIONS: The delusional confusion of dreamed events with reality is a prominent feature of narcolepsy, and suggests the possibility of source memory deficits in this disorder that have not yet been fully characterized.