Jaundice as the onset of paracoccidioidomycosis.

We report the case of a 24-year-old man from Brazil presenting with jaundice and epigastric pain. Abdominal CT and endoscopic ultrasound (EUS) revealed a mass in the pancreatic-duodenal groove, intrahepatic duct dilation, and lymphadenopathy, initially suggestive of lymphoproliferative syndrome. However, cytopathological analysis of EUS-guided fine needle aspiration (EUS-FNA) of the lymph nodes confirmed paracoccidioidomycosis. This case highlights the need to consider endemic mycoses, such as paracoccidioidomycosis, in the differential diagnosis of generalized lymphadenopathy, especially in patients from endemic regions.