[Acute complications of gastrointestinal stromal tumors].

OBJECTIVE

To analyze acute complications of stromal gastrointestinal tumors and determine diagnosis and optimal treatment of these patients.

MATERIAL AND

METHODS

There were 33 patients with acute complications of GIST aged 40-74 years.

RESULTS

Acute complications were presented by gastrointestinal and (or) intratumoral (interstitial) bleeding (n=31). Hemorrhage was combined with stomach perforation in 1 case, intussusception and obstruction of the duodenum in 1 patient, small bowel obstruction in 2 patients. All findings were confirmed by the marker CD 117 (+). One patient died in long-term period after R0-resection and chemotherapy. Targeted therapy was used in 2 patients.

CONCLUSION

Clinical examples indicate the progress in diagnosis and treatment of GIST due to development of instrumental imaging techniques, histological and histochemical verification of the process.