Turkish neurosurgery · 2014
Manic episode following deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Ugurlu Tugce Toker, Acar Goksemin, Karadag Filiz, Acar Feridun
Аннотация
AIM: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established therapy for patients with Parkinson's disease (PD) associated with motor complications of long term L-dopa treatment.
MATERIAL AND METHODS: Here we report two cases with DBS- induced manic episode, focusing on the functional and anatomic correlates of psychiatric adverse effects of STN stimulation.
RESULTS: We present two cases of PD with motor complications due to long term L-dopa treatment that developed their first episodes of mania with psychotic symptoms after bilateral STN-DBS implantation. DBS-induced psychiatric adverse effects may be attributable either to limbic connections and STN-specific oscillations or stimulation of the medial forebrain bundle.
MATERIAL AND METHODS: Here we report two cases with DBS- induced manic episode, focusing on the functional and anatomic correlates of psychiatric adverse effects of STN stimulation.
RESULTS: We present two cases of PD with motor complications due to long term L-dopa treatment that developed their first episodes of mania with psychotic symptoms after bilateral STN-DBS implantation. DBS-induced psychiatric adverse effects may be attributable either to limbic connections and STN-specific oscillations or stimulation of the medial forebrain bundle.