GMS hygiene and infection control · 2026
Acute mastoiditis caused by Klebsiella pneumoniae carbapenemase (KPC) producing bacteria - an atypical cause.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Aristodimou Aristos, Raptopoulos Zacharias, Georgiou Georgios, Xenofontos Elena, Dramiotou Loukia
Аннотация
AIM: The aim of this report is to present a rare case of acute mastoiditis caused by Klebsiella (K.) pneumoniae carbapenemase (KPC) producing bacteria.
METHODS: The following report describes a 78-year-old immunosuppressed female who was hospitalized due to left-sided acute otitis media complicated by tympanic membrane rupture and acute mastoiditis. Fluid-discharge culture revealed KPC. The patient successfully received four weeks of conservative treatment with intravenous colistin (based on antibiotic susceptibilities).
DISCUSSION: Acute mastoiditis is a rare complication of acute otitis media, mostly seen in pediatric populations. The most frequent causative agents identified are Gram-positive cocci such as Streptococcus (S.) pyogenes and S. pneumoniae. Acute mastoiditis caused by KPC-producing bacteria has rarely been reported in medical literature, with most such infections observed following neurosurgical surgeries and/or post-trauma.
CONCLUSION: The incidence of infection by KPC is rising, especially in immunosuppressed patients and those with recent and/or prolonged hospitalizations. There are very few reports in the literature describing acute mastoiditis caused by KPC. Infection with KPC not only has a high 30-day mortality rate (up to 40%) but also poses a significant financial burden on the healthcare system.
METHODS: The following report describes a 78-year-old immunosuppressed female who was hospitalized due to left-sided acute otitis media complicated by tympanic membrane rupture and acute mastoiditis. Fluid-discharge culture revealed KPC. The patient successfully received four weeks of conservative treatment with intravenous colistin (based on antibiotic susceptibilities).
DISCUSSION: Acute mastoiditis is a rare complication of acute otitis media, mostly seen in pediatric populations. The most frequent causative agents identified are Gram-positive cocci such as Streptococcus (S.) pyogenes and S. pneumoniae. Acute mastoiditis caused by KPC-producing bacteria has rarely been reported in medical literature, with most such infections observed following neurosurgical surgeries and/or post-trauma.
CONCLUSION: The incidence of infection by KPC is rising, especially in immunosuppressed patients and those with recent and/or prolonged hospitalizations. There are very few reports in the literature describing acute mastoiditis caused by KPC. Infection with KPC not only has a high 30-day mortality rate (up to 40%) but also poses a significant financial burden on the healthcare system.