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Медицинская библиотека · Acta reumatologica portuguesa · 2012

Position paper on tuberculosis screening in patients with immune mediated inflammatory diseases candidates for biological therapy.

Duarte R, Campainha S, Cotter J, Rosa B, Varela P, Correia A, Canhão H, Fonseca J E, Portuguese Society of Pulmonology, Portuguese Society of Gastroenterology, Portuguese Society of Dermatology and Venereology, Portuguese Society of Rheumatology

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Аннотация

UNLABELLED: Chronic immunosuppression is a known risk factor for tuberculosis. Our aim was to reach a consensus on screening and prevention of tuberculosis in patients with immune mediated inflammatory diseases candidates to biologic therapy.

METHODS

Critical appraisal of the literature and expert opinion on immunosuppressive therapies and risk of tuberculosis.

RESULTS AND

CONCLUSION

The currently recommended method for screening is the tuberculin skin test and the interferon gamma assay, after exclusion of active tuberculosis. Positively screened patients should be treated for latent tuberculosis infection. Patients may start biological therapy after 1 to 2 months, as long as they are strictly adhering to and tolerating their preventive regimen.

Для цитирования: Duarte R, Campainha S, Cotter J, Rosa B, Varela P, Correia A, Canhão H, Fonseca J E, Portuguese Society of Pulmonology, Portuguese Society of Gastroenterology, Portuguese Society of Dermatology and Venereology, Portuguese Society of Rheumatology. Position paper on tuberculosis screening in patients with immune mediated inflammatory diseases candidates for biological therapy.. Acta reumatologica portuguesa. 2012.

Предметные рубрики MeSH

Biological TherapyHumansImmune System DiseasesInflammationMass ScreeningTuberculosis
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