Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach.

BACKGROUND

Hypoplasminogenemia is a rare condition that is associated with ligneous conjunctivitis, a form of chronic conjunctivitis characterized by firm, fibrin-rich, pseudomembranous lesions on the tarsal conjunctivae and oral lesions. Pseudomembranes may develop on the gingivae, and there may be periodontal involvement.

METHODS

Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18-year-old girl.

RESULTS

This approach had no benefit.

CONCLUSION

The question remains about how best to manage patients with hypoplasminogenemia.