A Rare Type of Bullous Disorder in a Child. Can It Be Chronic Bullous Disease of Childhood?

Chronic bullous disease of childhood (CBDC), also known as childhood linear IgA bullous dermatosis, is a rare autoimmune disorder characterized by sub-epidermal blistering and linear deposition of immunoglobulin A at the demo-epidermal junction. Clinical manifestations in children include tense bulla (arranged annularly in the form of ring of pearl) and vesicles over the erythematous skin. Diagnosis is confirmed by skin biopsy from lesions showing sub-epidermal blisters in histopathological examination and linear deposition of IgA at the dermal-epidermal junction in direct immunofluorescence. Here, we report a case of CBDC in a 5-year-old child who was treated successfully with oral dapsone showing improvement in the skin lesions.