American journal of surgery · 2011
Prognostic factors after liver resection for hepatocellular carcinoma: a single-center experience from China.
Сравнительное исследованиеОценочное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Liu Liguo, Miao Ruoyu, Yang Huayu, Lu Xin, Zhao Yi, Mao Yilei, Zhong Shouxian, Huang Jiefu, Sang Xinting, Zhao Haitao
Аннотация
BACKGROUND: This study aimed to clarify the risk factors for survival and recurrence of hepatocellular carcinoma (HCC) in a cohort of Chinese HCC patients after hepatectomy and to compare 6 developed staging systems.
METHODS: A retrospective analysis was performed on 165 consecutive patients. The Kaplan-Meier method was used to calculate survival. Postoperative prognostic factors were evaluated using univariate and multivariate analyses. The overall predictive power of each staging system was evaluated by the area under the receiver operating characteristic curve.
RESULTS: The overall survival rates of 1, 3, and 5 years were 81.2%, 58.6%, and 56.7%, respectively, and the corresponding disease-free survival rates were 52.9%, 23.3%, and 15.5%, respectively. α-fetoprotein level and blood transfusion were correlated significantly with patients' overall survival, and portal vein thrombosis and tumor size (>5 cm) were correlated significantly with poor disease-free survival.
CONCLUSIONS: The French staging system is better for predicting the prognosis of HCC patients receiving surgical treatment.
METHODS: A retrospective analysis was performed on 165 consecutive patients. The Kaplan-Meier method was used to calculate survival. Postoperative prognostic factors were evaluated using univariate and multivariate analyses. The overall predictive power of each staging system was evaluated by the area under the receiver operating characteristic curve.
RESULTS: The overall survival rates of 1, 3, and 5 years were 81.2%, 58.6%, and 56.7%, respectively, and the corresponding disease-free survival rates were 52.9%, 23.3%, and 15.5%, respectively. α-fetoprotein level and blood transfusion were correlated significantly with patients' overall survival, and portal vein thrombosis and tumor size (>5 cm) were correlated significantly with poor disease-free survival.
CONCLUSIONS: The French staging system is better for predicting the prognosis of HCC patients receiving surgical treatment.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAntineoplastic AgentsCarcinoma, HepatocellularChemotherapy, AdjuvantChinaFemaleFollow-Up StudiesHepatectomyHumansLiver NeoplasmsMaleMiddle AgedMultivariate AnalysisNeoplasm Recurrence, LocalNeoplasm StagingROC CurveRetrospective StudiesRisk FactorsSurvival AnalysisTreatment Outcome