Mycopathologia · 2015
Evidence of Fluconazole-Resistant Candida Species in Tortoises and Sea Turtles.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Brilhante Raimunda Sâmia Nogueira, Rodrigues Pedro Henrique de Aragão, de Alencar Lucas Pereira, Riello Giovanna Barbosa, Ribeiro Joyce Fonteles, de Oliveira Jonathas Sales, Castelo-Branco Débora de Souza Collares Maia, Bandeira Tereza de Jesus Pinheiro Gomes, Monteiro André Jalles, Rocha Marcos Fábio Gadelha, Cordeiro Rossana de Aguiar, Moreira José Luciano Bezerra, Sidrim José Júlio Costa
Аннотация
The aim of this study was to evaluate the antifungal susceptibility of Candida spp. recovered from tortoises (Chelonoidis spp.) and sea turtles (Chelonia mydas, Caretta caretta, Lepidochelys olivacea, Eretmochelys imbricata). For this purpose, material from the oral cavity and cloaca of 77 animals (60 tortoises and 17 sea turtles) was collected. The collected specimens were seeded on 2% Sabouraud dextrose agar with chloramphenicol, and the identification was carried out by morphological and biochemical methods. Sixty-six isolates were recovered from tortoises, out of which 27 were C. tropicalis, 27 C. famata, 7 C. albicans, 4 C. guilliermondii and 1 C. intermedia, whereas 12 strains were obtained from sea turtles, which were identified as Candida parapsilosis (n = 4), Candida guilliermondii (n = 4), Candida tropicalis (n = 2), Candida albicans (n = 1) and Candida intermedia (n = 1). The minimum inhibitory concentrations for amphotericin B, itraconazole and fluconazole ranged from 0.03125 to 0.5, 0.03125 to >16 and 0.125 to >64, respectively. Overall, 19 azole-resistant strains (14 C. tropicalis and 5 C. albicans) were found. Thus, this study shows that Testudines carry azole-resistant Candida spp.