Chronic constipation in adults. How far should evaluation and treatment go?

In all patients who present with constipation, a history should be taken and physical examination and proctosigmoidoscopy performed. Structural evaluation of the entire colon by barium enema should be considered when constipation is of recent onset, is severe, or does not resolve with simple measures. A colonic transit study should also be considered in the latter two situations. Anorectal manometry, defecography, and electromyography are helpful in patients with diagnosed or suspected outlet delay. Treatment is most often empirical. Simple, helpful measures include education, dietary fiber supplementation, adequate fluid intake, and regular physical activity. When laxatives are necessary, they should be used sparingly. Pelvic floor retraining may be helpful in the management of patients with outlet delay. Select patients with intractable constipation may benefit from surgery, although results are variable.