American journal of Alzheimer's disease and other dementias · 2013
Predictors of cognitive decline in 85-year-old patients without cognitive impairment at baseline: 2-year follow-up of the octabaix study.
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Formiga Francesc, Ferrer Assumpta, Chivite David, Alburquerque Jesus, Olmedo Claudia, Mora Jose Maria, Labori María, Pujol Ramón, Octabaix study members
Аннотация
BACKGROUND/RATIONALE: To determine how many 85-year-old community-dwelling patients with good cognitive performance at baseline maintain this level at 2-year follow-up.
METHODS: We realized a longitudinal community-based study including 169 inhabitants. Patients who maintained scores >23 on the Spanish version of the Mini-Mental State Examination (MEC) were compared with the rest.
RESULTS: A total of 144 individuals (85.2%) were found maintaining a MEC score >23. Under the combined criteria 110 (65%) presented no new cognitive decline. Multiple logistic regression analysis showed that maintaining a MEC score >23 was significantly associated with having a higher MEC score at baseline (P < .001, odds ratio 1.280, 95% confidence interval 1.104-1.484).
CONCLUSION: Most oldest-old patients with good cognitive function at baseline maintain this level at 2-year follow-up.
METHODS: We realized a longitudinal community-based study including 169 inhabitants. Patients who maintained scores >23 on the Spanish version of the Mini-Mental State Examination (MEC) were compared with the rest.
RESULTS: A total of 144 individuals (85.2%) were found maintaining a MEC score >23. Under the combined criteria 110 (65%) presented no new cognitive decline. Multiple logistic regression analysis showed that maintaining a MEC score >23 was significantly associated with having a higher MEC score at baseline (P < .001, odds ratio 1.280, 95% confidence interval 1.104-1.484).
CONCLUSION: Most oldest-old patients with good cognitive function at baseline maintain this level at 2-year follow-up.