Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology · 2015
[The elevated levels of plasma chemerin and C-reactive protein in patients with acute coronary syndrome].
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Liang Zhishan, Yu Kunwu, Wu Bangwei, Zhong Yucheng, Zeng Qiutang
Аннотация
OBJECTIVE: To investigate the plasma levels of chemerin and C-reactive protein (CRP) in the patients with acute coronary syndrome.
METHODS: The plasma levels of chemerin and CRP were respectively measured by ELISA and immune luminescence sandwich assay in 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina (UA), 40 patients with stable angina (SA) and 40 control patients.
RESULTS: The levels of chemerin and CRP were significantly higher in the AMI and UA groups than in the SA and control groups, and the level of chemerin was significantly higher in the AMI group than in the UA group. The level of chemerin was positively correlated with the level of CRP, fasting glucose and left ventricular end-diastolic diameter, but negatively correlated with left ventricular ejection fraction.
CONCLUSION: The plasma levels of chemerin and CRP are elevated in patients with acute coronary syndrome.
METHODS: The plasma levels of chemerin and CRP were respectively measured by ELISA and immune luminescence sandwich assay in 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina (UA), 40 patients with stable angina (SA) and 40 control patients.
RESULTS: The levels of chemerin and CRP were significantly higher in the AMI and UA groups than in the SA and control groups, and the level of chemerin was significantly higher in the AMI group than in the UA group. The level of chemerin was positively correlated with the level of CRP, fasting glucose and left ventricular end-diastolic diameter, but negatively correlated with left ventricular ejection fraction.
CONCLUSION: The plasma levels of chemerin and CRP are elevated in patients with acute coronary syndrome.