Медицинская библиотека · American journal of public health · 1998

Serum ascorbic acid and other correlates of gallbladder disease among US adults.

Simon J A, Hudes E S

СтатьяПоддержка исследования: вне правительства СШАПоддержка службы здравоохранения СШАПеревод пока не подготовлен

Аннотация

OBJECTIVES

This study examined the correlates of clinical gallbladder disease among US adults and whether serum ascorbic acid levels are associated with a decreased prevalence of gallbladder disease.

METHODS

Cross-sectional analyses of data from the Second National Health and Nutrition Examination Survey were conducted.

RESULTS

A total of 384 women (8%) and 107 men (3%) reported a history of gallstone disease, and 347 women (7%) and 81 men (2%) reported a history of cholecystectomy. An inverted U-shaped relation was found between serum ascorbic acid level and clinical gallbladder disease among women but not among men.

CONCLUSIONS

Ascorbic acid, which affects the catabolism of cholesterol to bile acids and, in turn, the development of gallbladder disease in experimental animals, may reduce the risk of clinical gallbladder disease in humans.

Для цитирования: Simon J A, Hudes E S. Serum ascorbic acid and other correlates of gallbladder disease among US adults.. American journal of public health. 1998. DOI: 10.2105/ajph.88.8.1208.

Предметные рубрики MeSH

Adult Aged Ascorbic Acid Causality Cholecystectomy Cholelithiasis Cross-Sectional Studies Female Humans Incidence Male Middle Aged Sex Factors United States

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