Commentary on an article by Hannu T. Aro, MD, PhD, et al.: "Recombinant human bone morphogenetic protein-2: a randomized trial in open tibial fractures treated with reamed nail fixation".

This commentary was updated on April 15, 2011, because of a previous error. In the third paragraph, the sentence that had previously read “In the SPRINT, the two groups of open fractures were associated with statistically equivalent reoperation rates, but there was a trend toward better healing in the open fracture group treated with reamed intramedullary nailing.” now reads “In the SPRINT, the two groups of open fractures were associated with statistically equivalent reoperation rates, but there was a trend toward better healing in the open fracture group treated with unreamed intramedullary nailing.”