[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
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Jaeschke Lina, Steinbrecher Astrid, Greiser Karin Halina, Dörr Marcus, Buck Thomas, Linseisen Jakob, Meisinger Christa, Ahrens Wolfgang, Becher Heiko, Berger Klaus, Braun Bettina, Brenner Hermann, Castell Stefanie, Fischer Beate, Franzke Claus-Werner, Gastell Sylvia, Günther Kathrin, Hoffmann Wolfgang, Holleczek Bernd, Jagodzinski Annika, Kaaks Rudolf, Kluttig Alexander, Krause Gérard, Krist Lilian, Kuß Oliver, Lehnich Anna-Therese, Leitzmann Michael, Lieb Wolfgang, Löffler Markus, Michels Karin B, Mikolajczyk Rafael, Peters Annette, Schikowski Tamara, Schipf Sabine, Schmidt Börge, Schulze Matthias, Völzke Henry, Willich Stefan N, Pischon Tobias
Аннотация
OBJECTIVES: To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort.
MATERIALS AND METHODS: Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data.
RESULTS: With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany.
CONCLUSIONS: In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.