Unilateral Extremity Swelling, a Rare Manifestation of Scleredema Adultorum of Buschke in a Child: Case Report.

Scleredema adultorum of Bushcke is a rare connective tissue disorder that is characterized by skin thickening that commonly starts from the neck and spreads to the face, shoulders, upper back, abdomen, and in some cases, thighs. The symptoms are generally seen after an infection associated with streptococcus. Atypical clinical manifestations of the disease have been reported in a 13-year-old boy, who developed unilateral lower extremity swelling of the right thigh and leg and was admitted to the hospital with the primary diagnosis of Deep vein thrombosis (DVT). The ultimate diagnosis of scleredema adultorum of Buschke with an uncommon manifestation was established based on the clinical symptoms and ASO titers. This case has been reported to emphasize the importance of the unique signs and symptoms of the disease, leading to uncommon differential diagnosis which requires extensive investigation.