Alzheimer's & dementia : the journal of the Alzheimer's Association · 2011
Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010.
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Khachaturian Zaven S, Petersen Ronald C, Snyder Peter J, Khachaturian Ara S, Aisen Paul, de Leon Mony, Greenberg Barry D, Kukull Walter, Maruff Paul, Sperling Reisa A, Stern Yaakov, Touchon Jacques, Vellas Bruno, Andrieu Sandrine, Weiner Michael W, Carrillo Maria C, Bain Lisa J
Аннотация
The fourth Leon Thal Symposium (LTS2010) was convened in Toulouse, France, on November 3, 2010. This symposium reviewed design parameters that are necessary to develop comprehensive national databases on healthy aging. Such datasets offer the potential to serve as the foundation for a systems-approach to solve the dual public health problems of: (1) early detection of people who are at elevated risk for Alzheimer's disease, and (2) the development of interventions to delay onset of, or prevent, late-life dementia. The symposium considered three interrelated components of a National Database for Longitudinal Studies on Healthy Aging as follows: (a) a registry of healthy aging adults; (b) refined computer-based assessments for data gathering, including assessments of behavioral/memory changes associated with aging that are appropriate for broad use in nonexpert settings; and (c) high performance computing/supercomputer-based approaches for health data modeling and mining.