Heal and seal using injectable blood derivative: Case series.

Regenerative endodontic procedures initially proposed for dental pulp revascularisation in immature permanent tooth resulted in continued root development, increase thickness of dentinal wall and apical closure. Recently with increased knowledge, REP have been used to successfully treat mature permanent tooth with infected necrotic pulp and apical periodontitis. In present Case series two visit revascularisation procedure was performed by placing I-PRF in the root canals. A 3-mm plug of mineral trioxide aggregate was placed to seal the coronal orifice over semicoagulated blood. The access cavities were restored with composite resin. Followups of the treated cases was done using CBCT as measuring tool to evaluate the successful treatment outcome. There was evident reduction in size of lesion. Clinical signs and symptoms were absent in both cases at followup visits at different time intervals. The purpose of this series was to present the potential of using I-PRF as an alternative and promising treatment approach for management of mature teeth with chronic apical periodontitis.