Generalized Cryptococcus albidus in an immunosuppressed patient with palmopustular psoriasis.

Cryptococcal infection is relatively uncommon, except among immunocompromised individuals. The most common human pathogenic species is Cryptococcus neoformans. Virtually all organs can be affected, particularly the central nervous and pulmonary systems. The prototypical manifestations of cutaneous cryptococcal infection include generalized papules, periorificial acneiform pustules, and molluscumlike vesicles on the upper body. We describe an unusual case of Cryptococcus albidus infection presenting atypically with generalized hemorrhagic plaques. Furthermore, we review the literature on diagnostic evaluation and treatment.