[Juxtaglomerular cell tumor (reninoma) as the etiology of severe juvenile hypertension].

HISTORY AND CLINICAL FINDINGS: A 20-year-old asymptomatic man was admitted with severe hypertension (250/150 mm Hg). Clinical examination was normal.

INVESTIGATIONS: Laboratory findings showed hypokalemia and secondary hyperaldosteronism. Abdominal ultrasound and CT-scan revealed an about 2.5 cm measuring tumor of the left kidney.

TREATMENT AND COURSE: Under antihypertensive treatment, a normal blood pressure profile could be achieved. With the diagnosis of a reninoma the patient was transferred to the urology department for tumor resection. In a 3-month follow-up the patient was normotensive without any medication.

CONCLUSION

Renin-secreting juxtaglomerular tumor of the kidney (reninoma) is a very rare but curable cause of severe hypertension. The syndrome of "primary hyperreninism" is characterized by severe hypertension, hypokalemia, secondary hyperaldosteronism and a renal mass in sonography.