Photodiagnosis and photodynamic therapy · 2026
Precision conversion of colorectal cancer lung metastases: A personalized quadruplet regimen integrating photodynamic therapy with targeted, immunotherapy, and chemotherapy.
СтатьяКлинический случайНазвание и аннотация: Перевод пока не подготовлен
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Han Qinying, Gao Lei, Wang Yunpeng, Wang Zhuanfang, He Lijuan, Liu Ben, Hu Jike, Xu Bo, Chen Hao
Аннотация
SIGNIFICANCE: Colorectal cancer (CRC) has a high incidence and mortality rate, with lung metastasis being the second most common site. Current treatments have limited efficacy, and novel approaches are needed.
APPROACH: We report a case of a middle-aged female with CRC and lung metastasis treated with four cycles of PDT and five cycles of systemic therapy, including chemotherapy, targeted therapy, and immunotherapy.
RESULTS: After treatment, the lung metastases showed cystic changes, and the primary tumor significantly regressed (TRG: AJCC 0, Becker 1a). The patient successfully underwent surgical treatment.
CONCLUSIONS: This multimodal therapy shows promise in CRC lung metastasis, offering new insights for treatment.
APPROACH: We report a case of a middle-aged female with CRC and lung metastasis treated with four cycles of PDT and five cycles of systemic therapy, including chemotherapy, targeted therapy, and immunotherapy.
RESULTS: After treatment, the lung metastases showed cystic changes, and the primary tumor significantly regressed (TRG: AJCC 0, Becker 1a). The patient successfully underwent surgical treatment.
CONCLUSIONS: This multimodal therapy shows promise in CRC lung metastasis, offering new insights for treatment.