Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2006
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model].
СтатьяНазвание и аннотация: Перевод в очереди
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Zhao Xiao-Qin, Meng Shu, Wu Ya-Fei, Chen Yu, Ge Song
Аннотация
OBJECTIVE: To investigate the expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model at different stages of inflammation of varied severity.
METHODS: The periodontal tissues were immunohistochemically stained by antibody of MMP-2 and MMP-3.
RESULTS: MMP-2 and MMP-3 were both strongly positive in gingival epithelia and fibroblasts in periodontal ligament in rat periodontitis model. And chronic periodontitis showed lower expression of MMP-2 and MMP-3 than that of acute gingivitis and acute peridontitis.
CONCLUSION: The expression of MMP-2 and MMP-3 varies in different stage of periodontitis. MMP-2 and MMP-3 may play an important role in development of periodontitis.
METHODS: The periodontal tissues were immunohistochemically stained by antibody of MMP-2 and MMP-3.
RESULTS: MMP-2 and MMP-3 were both strongly positive in gingival epithelia and fibroblasts in periodontal ligament in rat periodontitis model. And chronic periodontitis showed lower expression of MMP-2 and MMP-3 than that of acute gingivitis and acute peridontitis.
CONCLUSION: The expression of MMP-2 and MMP-3 varies in different stage of periodontitis. MMP-2 and MMP-3 may play an important role in development of periodontitis.