Uso de una matriz autóloga en el tratamiento de úlceras de pie diabético, con espectroscopia de infrarrojo cercano y medidor de pH dérmico.

OBJECTIVE

Evaluate the efficiency of an autologous whole blood clot (WBC) matrix on diabetic foot ulcers (DFU), and analyse its immune response with near-infrared spectroscopy (NIRS) and pH measurement.

METHOD: Three patients were treated with a WBC. The matrix was produced at the point of care, using a WBC system. A WBC gel was formed and applied onto the wounds. The gel remained in place with primary and secondary dressings.

RESULTS

Wound-size reduction was 70% after two applications, 97.6% after three applications, and 90.9% after four applications. The NIRS skeletal muscle oxygen saturation (StO2) increased in all cases.

CONCLUSION

The autologous matrix was efficient in treating DFU. The wound area surface reduced after each application and wound healing was achieved in all cases. More studies are needed to understand the benefits of using a WBC matrix on DFU.