Voprosy pitaniia · 1992
[Increasing the effectiveness of thiamine by its administration together with methionine and vitamin E].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Parkhomenko Iu M, Chernysh I Iu, Protasova Z S, Donchenko G V
Аннотация
The influence of methionine and vitamin E, compounds intensifying thiol metabolism, on thiamine-phosphate level and thiamine-dependent dehydrogenase activity was studied in the liver of rats with varying thiamine providing: in case of its alimentary deficiency, and intensified thiamine consumption due to rat feeding with high-carbohydrate food. Methionine administration to vitamin B1-deficient rats led to a significant rise in thiamine-phosphate content and normalized alpha-ketoacid dehydrogenase acidity and non-protein SH-group level. Combined administration of thiamine with methionine and vitamin E increased the level of parameters studied. Methionine and vitamin E administered with thiamine intensified the regulatory action of thiamine on pyruvate dehydrogenase activity in the animals fed high-carbohydrate ration.