Toxic epidermal necrolysis.

Toxic epidermal necrolysis (TEN) is a potentially severe mucocutaneous affliction whose cause is usually drug related. TEN results in skin sloughing that resembles a partial thickness thermal injury. If the exposed dermis can be protected from infection, regeneration can occur. Podiatric surgeons are commonly involved in the management of lower extremity infections and utilize antibiotics, both orally and parenterally. This case study and review will familiarize the podiatric surgeon with the potential complications associated with drug-related interventions.