[Interstitial thiamine redistribution during the development of vitamin B1 deficiency in mice].

Investigation of diphosphothiamine content in the mouse tissues, associated with transketolase activity in the dynamic dependence on the body provision with vitamin B1, has proved the organ-specificity of deposition and elimination of diphosphothiamine under conditions of developing thiamine deficiency. The experimental data have evidenced that vitamin B1 exclusion from the food ration results in the diphosphothiamine redistribution between the tissues and in the provision with coenzymes of one tissue at the expense of the other.