Gan to kagaku ryoho. Cancer & chemotherapy · 2023
[A Case of Conversion Surgery after Long-Term Chemotherapy for Pancreatic Cancer with Peritoneal Metastasis].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Enoki Michihiro, Gotoh Kunihito, Sakai Kenji, Toshiyama Reishi, Yanagisawa Kiminori, Kawai Kenji, Miyo Masaaki, Takahashi Yusuke, Hamakawa Takuya, Doi Takashi, Takeno Atsushi, Katoh Takeshi, Takami Koji, Hirao Motohiro
Аннотация
A 66-year-old woman was referred to the gastroenterology division of our hospital due to elevation of serum CEA level. Contrast-enhanced CT showed a hypovascular tumor at the body of pancreas. She was diagnosed with pancreatic cancer by EUS-FNA. By laparotomy, we found white nodules on mesentery and abdominal wall, which were diagnosed as peritoneal metastasis. After systemic chemotherapy with 9 courses of gemcitabine(GEM)plus nab-paclitaxel(PTX)and 30 courses of mFOLFIRINOX, the tumor had shrunk and serum CA19-9 level were remarkably decreased. Distal pancreatectomy was performed as conversion surgery. Pathological analysis revealed no remnant cancer cells in the primary tumor or the lymph nodes, confirming a pCR. S-1 was started as adjuvant chemotherapy, and she remains alive without recurrence 8 months after surgery.