Seizures as an Initial Manifestation of Severe Anaphylaxis Following Intrathecal Contrast Injection: A Case Report.

Severe anaphylaxis is an acute allergic reaction that can be life-threatening if not managed rapidly. Its clinical manifestations are diverse, typically including hypotension, respiratory failure, and skin manifestations. However, seizures are an uncommon presentation and may easily be overlooked. We report a case of severe anaphylaxis following intrathecal injection of a contrast agent used in the evaluation of brachial plexus injuries. The initial manifestations were seizures and hypotension, occurring 15 min after injection. The patient survived following appropriate treatment and was subsequently discharged.