Serum-gamma-glutamyltranspeptidase (gamma-GT) and aspartate-aminotransferase (AspAT) activities in adult cattle with chronic Fasciola hepatica infection.

Sera from adult cattle with fluke-infected and normal livers were analyzed for γ-GT and AspAT activities. The analyses revealed no significant increases in either γ-GT or AspAT values of the animals with fascioliasis as compared with the non-infected animals. The advanced chronic stage of the infection characterized by hepatic fibrosis, limited injury of parenchyma and low fluke burdens may explain the lack of enzymatic increase.