Dermatitis : contact, atopic, occupational, drug · 2013
Persistent photosensitivity after allergic contact dermatitis to epoxy resin.
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Kwok Tiffany, Rosen Cheryl F, Storrs Frances J, Lobel Edmund, DeKoven Joel G
Аннотация
BACKGROUND: Persistent photosensitivity after allergic contact dermatitis (ACD) to epoxy resin has rarely been described.
OBJECTIVE: The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity.
METHODS: We present a series of 5 patients who developed ACD to epoxy resin and later a photodistributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB.
RESULTS: The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases. Patch testing to epoxy resin was positive in all patients. Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy.
CONCLUSIONS: There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.
OBJECTIVE: The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity.
METHODS: We present a series of 5 patients who developed ACD to epoxy resin and later a photodistributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB.
RESULTS: The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases. Patch testing to epoxy resin was positive in all patients. Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy.
CONCLUSIONS: There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.