Медицинская библиотека · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023

Mechanical thrombectomy in patients with heart failure: the Italian registry of Endovascular Treatment in Acute Stroke.

Gentile Luana, Pracucci Giovanni, Saia Valentina, Falcou Anne, Biraschi Francesco, Zini Andrea, Simonetti Luigi, Riva Letizia, Bigliardi Guido, Vallone Stefano, Nencini Patrizia, Limbucci Nicola, Diomedi Marina, Da Ros Valerio, Longoni Marco, Ruggiero Maria, Tassinari Tiziana, Allegretti Luca, Cerrato Paolo, Rubino Elisa, Bergui Mauro, Cavallo Roberto, Naldi Andrea, Comelli Chiara, Cappellari Manuel, Zivelonghi Cecilia, Plebani Mauro, De Vito Alessandro, Merli Nicola, Saletti Andrea, Musolino Rosa Fortunata, Ferraù Ludovica, Vinci Sergio Lucio, Sacco Simona, Orlandi Berardino, De Santis Federica, Filauri Pietro, Ruiz Luigi, Sepe Federica Nicoletta, Gallesio Ivan, Petruzzellis Marco, Chiumarulo Luigi, Sangalli Davide, Salmaggi Andrea, Filizzolo Marco, Moller Jessica, Melis Maurizio, Comelli Simone, Magoni Mauro, Gilberti Nicola, Gasparotti Roberto, Invernizzi Paolo, Pavia Marco, Pinto Vincenza, Laspada Salvatore, Marcheselli Simona, Ajello Daniele, Viaro Federica, Baracchini Claudio, Causin Francesco, Giannini Nicola, Caselli Maria Chiara, Mancuso Michelangelo, Cosottini Mirco, Scoditti Umberto, Menozzi Roberto, Russo Monia, Amistá Pietro, Napoletano Rosa, Romano Daniele Giuseppe, Tassi Rossana, Bracco Sandra, Carimati Federico, Versino Maurizio, Giorgianni Andrea, De Boni Antonella, Fasano Antonio, Barbarini Leonardo, Paladini Adriana, Franchini Enrica, Dall'Ora Elisa, Comai Alessio, Giovanni Frisullo, Pedicelli Alessandro, Sallustio Fabrizio, Casetta Ilaria, Fainardi Enrico, Mangiafico Salvatore, Toni Danilo, Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS) Collaborators

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Аннотация

BACKGROUND

Heart failure (HF) is the second most important cardiac risk factor for stroke after atrial fibrillation (AF). Few data are available on mechanical thrombectomy (MT) in acute ischemic stroke (AIS) patients with HF.

METHODS

The source of data is the multicentre Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS). All AIS patients ≥ 18 years receiving MT were categorised in two groups: HF and no-HF. Baseline clinical and neuroradiological findings on admission were analysed.

RESULTS

Of 8924 patients, 642 (7.2%) had HF. Compared to the no-HF group, HF patients had higher prevalence of cardiovascular risk factors. Rate of complete recanalisation (TICI 2b-3) was 76.9% in HF vs 78.1% in no-HF group (p = 0.481). Rate of symptomatic intracerebral haemorrhage at 24-h non-contrast computed tomography (NCCT) was 7.6% in HF vs 8.3% in no-HF patients (p = 0.520). At 3 months, 36.4% of HF patients and 48.2% of no-HF patients (p < 0.001) had mRS 0-2, and mortality was, respectively, 30.7% and 18.5% (p < 0.001). In multivariate logistic regression, HF was independently associated with mortality at 3 months (OR 1.53, 1.24-1.88 95% CI, p < 0.001). In multivariate ordinal regression, HF patients had a probability of transitioning to a higher mRS level of 1.23 (1.05-1.44 95% CI, p = 0.012). The propensity score analysis of two groups matched for age, sex, and NIHSS at admission yielded the same results.

CONCLUSION

MT is safe and effective in HF patients with AIS. Patients with HF and AIS suffered from higher 3-month mortality and unfavourable outcome regardless of acute treatments.

Для цитирования: Gentile Luana, Pracucci Giovanni, Saia Valentina, Falcou Anne, Biraschi Francesco, Zini Andrea, Simonetti Luigi, Riva Letizia, Bigliardi Guido, Vallone Stefano, Nencini Patrizia, Limbucci Nicola, Diomedi Marina, Da Ros Valerio, Longoni Marco, Ruggiero Maria, Tassinari Tiziana, Allegretti Luca, Cerrato Paolo, Rubino Elisa, Bergui Mauro, Cavallo Roberto, Naldi Andrea, Comelli Chiara, Cappellari Manuel, Zivelonghi Cecilia, Plebani Mauro, De Vito Alessandro, Merli Nicola, Saletti Andrea, Musolino Rosa Fortunata, Ferraù Ludovica, Vinci Sergio Lucio, Sacco Simona, Orlandi Berardino, De Santis Federica, Filauri Pietro, Ruiz Luigi, Sepe Federica Nicoletta, Gallesio Ivan, Petruzzellis Marco, Chiumarulo Luigi, Sangalli Davide, Salmaggi Andrea, Filizzolo Marco, Moller Jessica, Melis Maurizio, Comelli Simone, Magoni Mauro, Gilberti Nicola, Gasparotti Roberto, Invernizzi Paolo, Pavia Marco, Pinto Vincenza, Laspada Salvatore, Marcheselli Simona, Ajello Daniele, Viaro Federica, Baracchini Claudio, Causin Francesco, Giannini Nicola, Caselli Maria Chiara, Mancuso Michelangelo, Cosottini Mirco, Scoditti Umberto, Menozzi Roberto, Russo Monia, Amistá Pietro, Napoletano Rosa, Romano Daniele Giuseppe, Tassi Rossana, Bracco Sandra, Carimati Federico, Versino Maurizio, Giorgianni Andrea, De Boni Antonella, Fasano Antonio, Barbarini Leonardo, Paladini Adriana, Franchini Enrica, Dall'Ora Elisa, Comai Alessio, Giovanni Frisullo, Pedicelli Alessandro, Sallustio Fabrizio, Casetta Ilaria, Fainardi Enrico, Mangiafico Salvatore, Toni Danilo, Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS) Collaborators. Mechanical thrombectomy in patients with heart failure: the Italian registry of Endovascular Treatment in Acute Stroke.. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023. DOI: 10.1007/s10072-023-06830-9.

Предметные рубрики MeSH

Humans Ischemic Stroke Thrombectomy Treatment Outcome Stroke Heart Failure Registries Retrospective Studies Brain Ischemia Endovascular Procedures

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