[Molecular diagnosis of hand eczema].

BACKGROUND

Because hand eczema is a diagnostic challenge even for experienced dermatologists, a correct diagnosis is essential to ensure success of specific therapies.

OBJECTIVES

Prerequisites for successful molecular diagnostics in general and in hand eczema in particular are discussed.

MATERIALS AND

METHODS

Basic research and opinion statement on new developments in molecular diagnostics are considered with a special focus on hand eczema.

RESULTS

The first molecular classifier to distinguish psoriasis from (hand) eczema signature has been introduced as CE-marked in vitro diagnostics (CE-IVD); many more biomarkers associated with diagnostics, theranostics, or natural course of the disease are currently being investigated.

CONCLUSIONS

Diagnosis of hand eczema will be supported by molecular diagnostics in the near future; we are at the beginning of the molecular era in dermatology.