Lymphoreticular neoplasia in the nose.

A clinical-pathological discussion of three lymphoreticular neoplastic disease is presented, with illustrative case histories. These are 1. malignant midline reticulosis; 2. extramedullary plasmacytoma; 3. histiocytic lymphoma. Responsibility for exact diagnosis rests with the otolaryngologist to provide accurate and representative biopsy material for the pathologist. Because of the rarity of the disorders, the pathologist is entitled to repeat biopsies and consultations as needed. Although treatment is at the hands of others -- oncologists and radiation therapists -- the examining expertise of the otolaryngologist is essential in the care of these patients.