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DOI 10.2807/1560-7917.es.2020.25.13.2000305

Медицинская библиотека · Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020

Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe.

Stefanelli Paola, Faggioni Giovanni, Lo Presti Alessandra, Fiore Stefano, Marchi Antonella, Benedetti Eleonora, Fabiani Concetta, Anselmo Anna, Ciammaruconi Andrea, Fortunato Antonella, De Santis Riccardo, Fillo Silvia, Capobianchi Maria Rosaria, Gismondo Maria Rita, Ciervo Alessandra, Rezza Giovanni, Castrucci Maria Rita, Lista Florigio, ISS COVID-19 study group

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Аннотация

Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Italian, were compared with sequences from Europe and elsewhere. In a phylogenetic tree, the Italian patient's sequence clustered with sequences from Germany while the tourist's sequence clustered with other European sequences. Some additional European sequences in the tree segregated outside the two clusters containing the patients' sequences. This suggests multiple SARS-CoV-2 introductions in Europe or virus evolution during circulation.

Для цитирования: Stefanelli Paola, Faggioni Giovanni, Lo Presti Alessandra, Fiore Stefano, Marchi Antonella, Benedetti Eleonora, Fabiani Concetta, Anselmo Anna, Ciammaruconi Andrea, Fortunato Antonella, De Santis Riccardo, Fillo Silvia, Capobianchi Maria Rosaria, Gismondo Maria Rita, Ciervo Alessandra, Rezza Giovanni, Castrucci Maria Rita, Lista Florigio, ISS COVID-19 study group. Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe.. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2020. DOI: 10.2807/1560-7917.es.2020.25.13.2000305.

Предметные рубрики MeSH

BetacoronavirusCOVID-19ChinaCoronavirusCoronavirus InfectionsGenome, ViralGermanyHumansItalyMolecular EpidemiologyPandemicsPhylogenyPneumonia, ViralPoint MutationRNA, ViralSARS-CoV-2Severe Acute Respiratory SyndromeTravelWhole Genome Sequencing
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