Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery · 2016
[Surgical management of primary hyperthyroidism and coexistent thyroid carcinoma].
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Shen H, Wei B B, Xie H, Peng Z X, Wang J, Bai J
Аннотация
OBJECTIVE: To evaluated the results of surgical treatment for primary hyperparathyroidism coexistent with thyroid cancer.
METHODS: From March 2007 to May 2014, 27 patients suffered thyroid carcinoma coexistent with primary hyperparathyroidism with pathological and laboratory confirmation were studied retrospectively. In 8 of 27 cases thyroidectomy and parathyroidectomy were performed separately, with interval time of 3 to 26 months, and in the remaining cases both procedures were done simultaneously. During surgery quick PTH evaluation and calcium measure were routinely performed.
RESULTS: Postoperative temporary hypoparathyroidism was found in 26 of 27 cases, and postoperative permanent hypoparathyroidism developed in 4 cases that underwent separate operation. Limited movement of vocal cord was showed in 4 cases after parathyroidectomy, but it lasted no more than 2 months. No permanent paralysis of recurrent laryngeal nerve was found. No thyroid cancer or hyperparathyroidism was found with follows-up of 11 to 43 months.
CONCLUSIONS: Thyroidectomy and parathyroidectomy performed separately have higher risk to develop hypoparathyroidism than they are done simultaneously. PTH and calcium should be evaluated in patients with thyroid carcinoma whenever available.
METHODS: From March 2007 to May 2014, 27 patients suffered thyroid carcinoma coexistent with primary hyperparathyroidism with pathological and laboratory confirmation were studied retrospectively. In 8 of 27 cases thyroidectomy and parathyroidectomy were performed separately, with interval time of 3 to 26 months, and in the remaining cases both procedures were done simultaneously. During surgery quick PTH evaluation and calcium measure were routinely performed.
RESULTS: Postoperative temporary hypoparathyroidism was found in 26 of 27 cases, and postoperative permanent hypoparathyroidism developed in 4 cases that underwent separate operation. Limited movement of vocal cord was showed in 4 cases after parathyroidectomy, but it lasted no more than 2 months. No permanent paralysis of recurrent laryngeal nerve was found. No thyroid cancer or hyperparathyroidism was found with follows-up of 11 to 43 months.
CONCLUSIONS: Thyroidectomy and parathyroidectomy performed separately have higher risk to develop hypoparathyroidism than they are done simultaneously. PTH and calcium should be evaluated in patients with thyroid carcinoma whenever available.