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Journal of hematology & oncology · 2018

The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China-recommendations from the Chinese Society of Hematology.

СтатьяПоддержка исследования: вне правительства СШАОбзорConsensus StatementНазвание и аннотация: Перевод пока не подготовлен
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Xu Lanping, Chen Hu, Chen Jing, Han Mingzhe, Huang He, Lai Yongrong, Liu Daihong, Liu Qifa, Liu Ting, Jiang Ming, Ren Hanyun, Song Yongping, Sun Zimin, Wang Jianmin, Wu Depei, Zhou Daobin, Zou Ping, Liu Kaiyan, Huang Xiaojun

Аннотация

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat malignant hematological neoplasms and non-malignant hematological disorders. Approximately, 5000 allo-HSCT procedures are performed in China annually. Substantial progress has been made in haploidentical HSCT (HID-HSCT), pre-transplantation risk stratification, and donor selection in allo-HSCT, especially after the establishment of the "Beijing Protocol" HID-HSCT system. Transplant indications for selected subgroups in low-risk leukemia or severe aplastic anemia (SAA) differ from those in the Western world. These unique systems developed by Chinese doctors may inspire the refining of global clinical practice. We reviewed the efficacy of allo-HSCT practice from available Chinese studies on behalf of the HSCT workgroup of the Chinese Society of Hematology, Chinese Medical Association and compared these studies to the consensus or guideline outside China. We summarized the consensus on routine practices of all-HSCT in China and focused on the recommendations of indications, conditioning regimen, and donor selection.

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