Evaluation of Post-Endodontic Pain Reduction Using Intracanal Cryotherapy in Symptomatic Apical Periodontitis.

This prospective experimental study evaluated the efficacy of intracanal cryotherapy in reducing postoperative pain in patients with symptomatic apical periodontitis. Ninety participants with necrotic pulp and preoperative pain (VAS ≥ 7) were randomised into two groups: Group A received room-temperature saline irrigation, while Group B received cryotreated saline (2.5°C) as the final irrigant. Pain was assessed preoperatively, at 24 h, and 48 h post-treatment using the Visual Analogue Scale. Results demonstrated significantly lower pain scores in the cryotherapy group at 24 h (p = 0.010) and 48 h (p < 0.001), with reduced analgesic use. Cryotherapy effectively mitigates post-operative pain in symptomatic apical periodontitis, offering a non-invasive adjunct to standard endodontic therapy.