Journal of pharmacy & bioallied sciences · 2025
Comparative Evaluation of the Efficacy of Mouthwash and Denture Cleanser in the Removal of Candida Albicans from Two Flexible Denture Base Materials - An In vitro Study.
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Teja B V H Ravi, Babu Jayakrishna, Sunkala Lokesh, Chander V Bhanu, Karthik K V Gurucharan, Alex Jisa A
Аннотация
BACKGROUND: Poly-methyl methacrylate is the most common denture base material but has limitations. Flexible denture base materials, such as Lucitone FRS and Valplast, were introduced to address these issues. Denture success depends on preventing microbial attachment and easy cleaning. This study evaluates the efficacy of Clinsodent denture cleanser and 0.2% Chlorhexidine (Rexidine) mouthwash in removing Candida albicans from these materials.
METHODOLOGY: Forty-eight specimens were subdivided into three groups, with eight in each. After inoculation with Candida albicans, samples were treated with distilled water (control), 0.2% Rexidine mouthwash, or Clinsodent cleanser. Colony counts were analyzed.
RESULTS: Rexidine mouthwash was more effective than Clinsodent. Valplast showed higher initial Candida growth, indicating Lucitone FRS is more resistant.
CONCLUSION: 0.2% Rexidine mouthwash was superior in Candida removal, and Lucitone FRS exhibited greater resistance than Valplast.
METHODOLOGY: Forty-eight specimens were subdivided into three groups, with eight in each. After inoculation with Candida albicans, samples were treated with distilled water (control), 0.2% Rexidine mouthwash, or Clinsodent cleanser. Colony counts were analyzed.
RESULTS: Rexidine mouthwash was more effective than Clinsodent. Valplast showed higher initial Candida growth, indicating Lucitone FRS is more resistant.
CONCLUSION: 0.2% Rexidine mouthwash was superior in Candida removal, and Lucitone FRS exhibited greater resistance than Valplast.