Journal of dentistry · 2025
Systematic review of antibacterial effects of nanoparticles in clear overlay orthodontic appliances: advancements in orthodontic treatment.
СтатьяСистематический обзорПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Abbass Noor Nourie, Zabidi Muhammad Azrul, Addie Ali J, Nahidh Mohammed, Noor Siti Noor Fazliah Mohd, Kamaruddin Anis Farhan
Аннотация
OBJECTIVE: Aesthetic orthodontic treatment, particularly with clear overlay appliances (COAs), is becoming increasingly popular. However, microbial accumulation and compromised oral hygiene during prolonged wear may lead to white-spot lesions, caries, and periodontal complications. These concerns have encouraged the exploration of nanotechnology-based alternatives, employing nanomaterials as broad-spectrum antimicrobial agents to prevent or mitigate bacterial growth, especially in orthodontics.This systematic review aims to analyse, summarise, and evaluate the available evidence on the integration of nanomaterials into COAs, with a focus on progress achieved, limitations regarding antibacterial effectiveness, and potential future directions in orthodontic therapy.
METHODS: A comprehensive search of PubMed, Scopus, and Web of Science databases was performed using specific keywords. Inclusion criteria focused on peer-reviewed studies addressing the antibacterial properties of nanomaterials incorporated into COAs. Data were extracted, and methodological quality was assessed using the Modified Joanna Briggs Institute Checklist for in vitro studies.
RESULTS: The initial search yielded 315 documents. Following record screening, nine articles were included. These studies investigated the antibacterial effects of nanoparticles (NPs) in various COAs.
CONCLUSION: This systematic review highlights the considerable antibacterial potential of NPs in COAs. Nevertheless, variability in study designs and outcomes emphasises the need for standardised protocols and further research to confirm clinical efficacy and long-term safety.
CLINICAL SIGNIFICANCE: The integration of NPs into COAs presents a promising strategy to reduce bacterial colonisation and biofilm formation. Such modifications could enhance oral hygiene, lower the risk of caries and gingival inflammation during orthodontic treatment, and support the long-term success of retention therapy.
METHODS: A comprehensive search of PubMed, Scopus, and Web of Science databases was performed using specific keywords. Inclusion criteria focused on peer-reviewed studies addressing the antibacterial properties of nanomaterials incorporated into COAs. Data were extracted, and methodological quality was assessed using the Modified Joanna Briggs Institute Checklist for in vitro studies.
RESULTS: The initial search yielded 315 documents. Following record screening, nine articles were included. These studies investigated the antibacterial effects of nanoparticles (NPs) in various COAs.
CONCLUSION: This systematic review highlights the considerable antibacterial potential of NPs in COAs. Nevertheless, variability in study designs and outcomes emphasises the need for standardised protocols and further research to confirm clinical efficacy and long-term safety.
CLINICAL SIGNIFICANCE: The integration of NPs into COAs presents a promising strategy to reduce bacterial colonisation and biofilm formation. Such modifications could enhance oral hygiene, lower the risk of caries and gingival inflammation during orthodontic treatment, and support the long-term success of retention therapy.