Special Considerations in Disease Manifestations and Management of Pemphigus in the Elderly.

Pemphigus, including its main subtypes of pemphigus vulgaris, pemphigus foliaceus and paraneoplastic autoimmune multiorgan syndrome (formally known as paraneoplastic pemphigus), is an autoimmune blistering disease which is characterized by acantholysis resulting from autoantibodies targeting epithelial cell surface antigens. Elderly patients with pemphigus face unique challenges pertaining to diagnostics and therapeutics. This review focuses on the special considerations which relate to the care of this patient group.