MedElevator Войти в исследования
← Поиск публикаций

DOI 10.1038/s41387-023-00234-6

Медицинская библиотека · Nutrition & diabetes · 2023

A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control.

Apolzan John W, LaRose Jessica Gokee, Anton Stephen D, Beyl Robbie A, Greenway Frank L, Wickham Edmond P, Lanoye Autumn, Harris Melissa N, Martin Corby K, Bullard Tiffany, Foster Gary D, Cardel Michelle I

Клиническое исследованиеСтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

BACKGROUND

The objective was to test the efficacy of a scalable, virtually delivered, diabetes-tailored weight management program on glycemic control in adults with type 2 diabetes (T2D).

METHODS

This was a single arm, three-site clinical trial. Participants had baseline HbA1c between 7-11% and BMI between 27-50 kg/m2. Primary outcome was change in HbA1c at 24 weeks. Secondary outcomes were changes in body weight, waist circumference, the Diabetes Distress Scale (DDS), quality of life (IWQOL-L), and hunger (VAS). Generalized linear effects models were used for statistical analysis.

RESULTS

Participants (n = 136) were 56.8 ± 0.8 y (Mean ± SEM), 36.9 ± 0.5 kg/m2, 80.2% female, 62.2% non-Hispanic white. Baseline HbA1c, weight, and total DDS score were 8.0 ± 0.09%, 101.10 ± 1.47 kg, and 2.35 ± 0.08, respectively. At week 24, HbA1c, body weight, and total DDS decreased by 0.75 ± 0.11%, 5.74 ± 0.50%, 0.33 ± 0.10 units, respectively (all p < 0.001). Also, at week 24, quality of life increased by 9.0 ± 1.2 units and hunger decreased by 14.3 ± 2.4 units, (both p < 0.0001).

CONCLUSIONS

The scalable, virtually delivered T2D-tailored weight management program had favorable and clinically meaningful effects on glycemic control, body weight, and psychosocial outcomes.

Для цитирования: Apolzan John W, LaRose Jessica Gokee, Anton Stephen D, Beyl Robbie A, Greenway Frank L, Wickham Edmond P, Lanoye Autumn, Harris Melissa N, Martin Corby K, Bullard Tiffany, Foster Gary D, Cardel Michelle I. A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control.. Nutrition & diabetes. 2023. DOI: 10.1038/s41387-023-00234-6.

Предметные рубрики MeSH

Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Тип публикации указан по данным источника. Уровень доказательности автоматически не присваивается.