Journal of diabetes and its complications · 2016
Carotid atherosclerosis progression and cerebrovascular events in patients with diabetes.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Vouillarmet Julien, Helfre Marjorie, Maucort-Boulch Delphine, Riche Benjamin, Thivolet Charles, Grange Claire
Аннотация
AIM: Carotid atherosclerosis progression is associated with a higher risk of cerebrovascular events but there is no specific data for diabetes. We assessed in a cohort of patients with diabetes the rate of atherosclerosis progression by Doppler ultrasonography and the association with cerebrovascular events.
METHODS: We analyzed a retrospective cohort of 342 patients with a mean duration of diabetes of 13.6 ± 10.6 years. The mean delay between the first and last Doppler ultrasonography was 6.4 ± 4.6 years, with a mean of 3.4 examinations per person. Cerebrovascular events were noted.
RESULTS: A progression of carotid atherosclerosis was observed in 20.1% of cases. No factor was significantly associated with progression. A prophylactic carotid endarterectomy was performed on 6 of the 27 patients with a stenosis ≥50%. A cerebrovascular event occurred in 1.2% of patients; none of them had carotid atherosclerosis progression.
CONCLUSIONS: Carotid atherosclerosis progression in patients with diabetes is frequent but surgical treatment and cerebrovascular events are low. The benefit of a systematic follow-up of carotid atherosclerosis seems limited.
METHODS: We analyzed a retrospective cohort of 342 patients with a mean duration of diabetes of 13.6 ± 10.6 years. The mean delay between the first and last Doppler ultrasonography was 6.4 ± 4.6 years, with a mean of 3.4 examinations per person. Cerebrovascular events were noted.
RESULTS: A progression of carotid atherosclerosis was observed in 20.1% of cases. No factor was significantly associated with progression. A prophylactic carotid endarterectomy was performed on 6 of the 27 patients with a stenosis ≥50%. A cerebrovascular event occurred in 1.2% of patients; none of them had carotid atherosclerosis progression.
CONCLUSIONS: Carotid atherosclerosis progression in patients with diabetes is frequent but surgical treatment and cerebrovascular events are low. The benefit of a systematic follow-up of carotid atherosclerosis seems limited.
Предметные рубрики MeSH
AdultAgedAtherosclerosisCarotid Artery DiseasesCerebrovascular DisordersCohort StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic AngiopathiesDisease ProgressionEndarterectomy, CarotidFemaleFollow-Up StudiesFranceHospitals, UrbanHumansMaleMiddle AgedPractice Patterns, Physicians'Retrospective StudiesRisk FactorsUltrasonography, Doppler, Duplex