Disseminated cryptococcosis in an immunocompetent farmer: A rare case report.

Cryptococcosis is an opportunistic fungal infection commonly occurring amongst immunocompromised individuals. However, in rare cases it can affect immunocompetent individuals particularly those with exposure to fungal reservoirs in environment. We report a 32-year-old immunocompetent male farmer who was diagnosed with disseminated cryptococcosis. He initially presented with prolonged cough, exertional dyspnoea and weight loss and later developed nodulo-ulcerative skin lesion and central nervous system cryptococcomas. The diagnosis was confirmed by histopathology and cryptococcal antigen testing. He was treated with liposomal amphotericin B and flucytosine, followed by maintenance fluconazole therapy. This case-report highlights the importance of keeping a high index of suspicion for disseminated cryptococcosis even in immunocompetent individuals.