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DOI 10.7554/elife.61121

Медицинская библиотека · eLife · 2020

The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion.

Collins Christine R, Hackett Fiona, Howell Steven A, Snijders Ambrosius P, Russell Matthew Rg, Collinson Lucy M, Blackman Michael J

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

BACKGROUND

Patients with complete bilateral cleft lip and palate (CBCLP) have the most complex orofacial abnormalities despite its lowest incidence among cleft lip and palate (CLP) types. Impaired maxillary growth can result from surgical procedures in patients with CBCLP. This study evaluates dental arch relationships in Indonesian patients with CBCLP after undergoing CLP repair at Harapan Kita Children and Mother Hospital in Jakarta.

MATERIAL AND

METHODS

Using the modified Huddart and Bodenham (MHB) index and Bauru bilateral cleft lip and palate (BCLP) yardstick, three examiners assessed 17 study models in the 9-year age group and 13 study models in the 12-year age group, as well as two intraoral clinical photographs of two patients with CBCLP. The assessments were repeated three times within two weeks of each assessment time.

RESULTS

Patients with operated CBCLP (aged 9 and 12 years) had edge-to-edge tooth relations, which were categorized as a mild crossbite or mild deviation, and only required orthodontic treatment according to the two specified indicators.

CONCLUSIONS

The CLP repair protocol used at the Harapan Kita Hospital effectively manages CBCLP cases with satisfactory results, suggesting the effectiveness of the MHB index and Bauru-BCLP yardstick in assessing dental arch relationships in patients with operated CBCLP. Key words:Bilateral, cleft lip and palate, dental arch relationship, lip repair, palate repair.

Для цитирования: Collins Christine R, Hackett Fiona, Howell Steven A, Snijders Ambrosius P, Russell Matthew Rg, Collinson Lucy M, Blackman Michael J. The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion.. eLife. 2020. DOI: 10.7554/elife.61121.

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