Transplant infectious disease : an official journal of the Transplantation Society · 2023
Respiratory virus infections after allogeneic stem cell transplantation: Current understanding, knowledge gaps, and recent advances.
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Piñana Jose L, Pérez Ariadna, Chorão Pedro, Guerreiro Manuel, García-Cadenas Irene, Solano Carlos, Martino Rodrigo, Navarro David, Infectious Complications Subcommittee of the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH-TC)
Аннотация
Before the COVID-19 pandemic, common community-acquired seasonal respiratory viruses (CARVs) were a significant threat to the health and well-being of allogeneic hematopoietic cell transplant (allo-HCT) recipients, often resulting in severe illness and even death. The pandemic has further highlighted the significant risk that immunosuppressed patients, including allo-HCT recipients, face when infected with SARS-CoV-2. As preventive transmission measures are relaxed and CARVs circulate again among the community, including in allo-HSCT recipients, it is crucial to understand the current state of knowledge, gaps, and recent advances regarding CARV infection in allo-HCT recipients. Urgent research is needed to identify seasonal respiratory viruses as potential drivers for future pandemics.