Reproductive sciences (Thousand Oaks, Calif.) · 2021
Gonadotropin-Releasing Hormone Agonist Versus Recombinant Human Chorionic Gonadotropin Triggering in Fertility Preservation Cycles.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Herzberger Einat Haikin, Knaneh Sabaa, Amir Hadar, Reches Adi, Ben-Yosef Dalit, Kalma Yael, Azem Foad, Samara Nivin
Аннотация
The purpose of this research is to study the efficacy of GnRH-a versus r-hCG triggering in patients who go through fertility preservation cycles. This retrospective cohort study was performed in a tertiary university-affiliated medical center. It includes 191 patients undergoing fertility preservation cycles between May 2013 and September 2018, in which ovulation was induced by either GnRH-a or r-hCG. Main outcome measures were number and rate of mature oocyte. Among treatment cycles with medical indication, GnRH agonist significantly increases the odds for high mature rate by 3.55 (1.30-9.66), while in treatment cycles with social indication, there is no significant effect of the triggering agent. An advantage for GnRH-a triggering was observed in medically indicated preservation cycles.