Internal medicine (Tokyo, Japan) · 2017
Insulinoma with a History of Epilepsy: Still a Possible Misleading Factor in the Early Diagnosis of Insulinoma.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Murakami Takaaki, Yamashita Takafumi, Yabe Daisuke, Masui Toshihiko, Teramoto Yuki, Minamiguchi Sachiko, Hirota Keisho, Ogura Masahito, Nagashima Kazuaki, Inagaki Nobuya
Аннотация
A delayed diagnosis of insulinoma remains a clinical issue. Hypoglycemic symptoms can mimic neuropsychiatric disorders such as epilepsy. A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval. She had received transient treatment with AEDs before the possibility of hypoglycemia was considered. Following a clinical diagnosis of insulinoma, distal pancreatectomy was performed; her seizures didn't occur again. The early diagnosis of insulinoma requires vigilance not only for hypoglycemia in patients with neuropsychiatric symptoms but also for the possible masking effects of a history of epilepsy and preceding AED usage.